In vitro inhibition of feline coronavirus replication by small interfering RNAs
نویسندگان
چکیده
منابع مشابه
Effect of small interfering RNAs on in vitro replication and gene expression of feline coronavirus.
OBJECTIVE To evaluate the ability of small interfering RNAs (siRNAs) to inhibit in vitro viral replication and gene expression of feline coronavirus (FCoV). SAMPLE Cell cultures of Crandell-Rees feline kidney cells. PROCEDURES 5 synthetic siRNAs that each targeted a different region of the FCoV genome were tested individually and in various combinations for their antiviral effects against 2...
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ژورنال
عنوان ژورنال: Veterinary Microbiology
سال: 2011
ISSN: 0378-1135
DOI: 10.1016/j.vetmic.2011.01.023